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My husband seems to not be able to focus much, i.e. not seeing things right around a room that might need his attention. He really doesn't want to listen or "tune in" to my questions and barks all too often--"what's wrong with you"? I am not a patient person and whatever I may have had is running on a thread at present but what in the heck is happening. Anyone have any ideas?

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Has he been diagnosed with something?
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Dementia-guide-dot-com is a great resource. If you check under the "learn" tab they have a symptom library.
"Although loss of initiative sometimes is present before the diagnosis of Alzheimer’s disease, it generally occurs in early dementia and becomes worse as the disease progresses."
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My first thought is stroke or continual small TIAs leading to sensory deficit or sensory inattention; but please note I may only think that because this happened with my mother - it's all too easy for a layman like me to think "snap!" when in fact there could be something completely different going on. Does your husband have any diagnosed health conditions at all?
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You say in your profile that he has had multiple tests, including an MRI. What does the neurologist say?
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